Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947591 | 0.85 | KDM4E (0.97) | KDM4EALDH1A1L3MBTL1TDP1HPGD | |
| SCHEMBL6770354 | 0.80 | ADRB1 (0.56) | KDM4EALDH1A1L3MBTL1TDP1HPGD | |
| Hydrochloric Acid SCHEMBL30222843 | 0.79 | ADRB1 (0.55) | KDM4EALDH1A1L3MBTL1TDP1HPGD | |
| SCHEMBL24970932 | 0.79 | TDP1 (0.54) | KDM4EALDH1A1L3MBTL1TDP1HPGD | |
| SCHEMBL6225002 | 0.79 | HTR6 (0.54) | KDM4EALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL24969918 | 0.79 | HTR3A (0.54) | KDM4EALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL31142864 | 0.79 | HTR3A (0.54) | KDM4EALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL24971049 | 0.79 | HTR6 (0.54) | KDM4EALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL16087144 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1TDP1HPGD | |
| SCHEMBL3441206 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368008-A1 | TRANSDERMAL THERAPEUTIC SYSTEM FOR THE ADMINISTRATION OF PARTIAL DOPAMINE-D2 AGONISTS | LTS Lohmann Therapie-Systeme AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002069941-A1 | TRANSDERMAL THERAPEUTIC SYSTEM FOR THE ADMINISTRATION OF PARTIAL DOPAMINE-D2 AGONISTS | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2002-09-12 | — | — | WO | disclosed |