Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078730 | 0.88 | ABCB1 (0.42) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL1850525 | 0.83 | ALDH1A1 (0.45) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL6581785 | 0.82 | ALDH1A1 (0.47) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL13494184 | 0.82 | ALDH1A1 (0.44) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL7282074 | 0.81 | CCR6 (0.48) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL801192 | 0.80 | CCR6 (0.54) | ALDH1A1CCR6PAX8MAPK1TDP1 | |
| SCHEMBL13049197 | 0.78 | CCR6 (0.50) | ALDH1A1CCR6PAX8MAPK1TDP1 | |
| SCHEMBL5729903 | 0.78 | ALDH1A1 (0.43) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL4693168 | 0.78 | CCR6 (0.45) | ABCB1ALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL11298253 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CCR6PAX8MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346994-A1 | CHOLESTEROL BIOSYNTHESIS INHIBITORS CONTAINING AS THE ACTIVE INGREDIENT TRICYCLIC SPIRO COMPOUNDS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |