Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660036 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL2059355 | 0.77 | CSNK2A2 (0.49) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL29200157 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL21254300 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL2113005 | 0.76 | PTGDR2 (0.64) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL3064143 | 0.76 | TSHR (0.70) | KDM4EALDH1A1HSD17B10PTGDR2TDP1 | |
| SCHEMBL5588261 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL6516217 | 0.76 | HPGD (0.62) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL320418 | 0.74 | PTGDR2 (0.66) | KDM4EPTGDR2TDP1TSHRPOLB | |
| SCHEMBL4364423 | 0.73 | PTGDR2 (0.46) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657052-B1 | Labeling DNA or RNA at a specific site consisting of stable precursor, and only becomes reactive upon activation; alkylating only phosphodiester groups; lactonization reaction traps the trialkylphosphate in a stable form. | UNIVERSITY OF ARKANSAS | 2003-12-02 | — | — | US | disclosed |