Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191607 | 0.88 | DHODH (0.49) | PTPN1LMNAHPGDTHRATHRB | |
| Zinc Ion SCHEMBL9191597 | 0.86 | MMP9 (0.45) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12771417 | 0.83 | PTPN1 (0.44) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10481838 | 0.82 | MAPT (0.50) | MAOBMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12771402 | 0.82 | PTPN1 (0.45) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6458856 | 0.81 | MEN1 (0.48) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL4784102 | 0.80 | MAOB (0.59) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7916872 | 0.80 | MAOB (0.52) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL14856441 | 0.79 | MAPT (0.55) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL27733164 | 0.79 | BRD4 (0.58) | PTPN1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657052-B1 | Labeling DNA or RNA at a specific site consisting of stable precursor, and only becomes reactive upon activation; alkylating only phosphodiester groups; lactonization reaction traps the trialkylphosphate in a stable form. | UNIVERSITY OF ARKANSAS | 2003-12-02 | — | — | US | disclosed |