Ether

Ether

SCHEMBL7262189

CC(Br)C(=O)O.CCOCC.N.N

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
TP53 P04637 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 2/20 0.35
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL7985620 0.97 ALDH1A1 (0.38) ALDH1A1THRBRECQLLCKPPARD
Ether SCHEMBL22264689 0.82 ALDH1A1 (0.36) ALDH1A1THRBTSHRTRPA1
Ether SCHEMBL8206941 0.81 TP53 (0.40) ALDH1A1TP53TSHRCHRM1AKR1A1
Ammonia Solution, Strong SCHEMBL28812796 0.81
Ammonia Solution, Strong SCHEMBL27970528 0.81
Ether SCHEMBL7265587 0.80 LMNA (0.36) ALDH1A1TP53TSHRCHRM1AKR1A1
Lactic Acid SCHEMBL1237356 0.79 TP53 (0.61) ALDH1A1TP53TSHRCHRM1AKR1A1
SCHEMBL2023600 0.78 LMNA (0.57) ALDH1A1THRBRECQLLCKPPARD
Ether SCHEMBL29058438 0.78 ALDH1A1 (0.43) ALDH1A1THRBTSHRHDAC1HDAC2
SCHEMBL233072 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6638349-B2 Reaction product of the simultaneous reaction of a halogenated carboxylic acid, a fatty acid and a polyamine; acid equivalents are equal to those of amines ATKINSON GEORGE K (US) 2003-10-28 US disclosed
US-20020129742-A1 Surface treatments for pigments providing improved dispersibility and exhibiting biocidal activity GEORGE K ATKINSON (US) 2002-09-19 US disclosed