Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8930737 | 0.97 | TP53 (0.58) | TP53ALDH1A1TSHRMEN1KMT2A | |
| Ether SCHEMBL8206941 | 0.86 | TP53 (0.40) | TP53ALDH1A1TSHRCHRM1AKR1A1 | |
| Ether SCHEMBL9389158 | 0.83 | TP53 (0.38) | TP53ALDH1A1TSHRCHRM1AKR1A1 | |
| Cadaverine Tartrate SCHEMBL2963333 | 0.83 | TSHR (0.56) | TP53ALDH1A1TSHRCHRM1AKR1A1 | |
| Lactic Acid SCHEMBL27721040 | 0.82 | — | — | |
| Ether SCHEMBL27969816 | 0.81 | ALDH1A1 (0.41) | TP53ALDH1A1TSHRTDP1FFAR3 | |
| Alanine SCHEMBL14688036 | 0.81 | GABRP (0.42) | TP53ALDH1A1 | |
| Lactic Acid SCHEMBL28243129 | 0.81 | TP53 (0.58) | TP53ALDH1A1CHRM1AKR1A1CHRM3 | |
| Ether SCHEMBL7985620 | 0.81 | ALDH1A1 (0.38) | TP53ALDH1A1TSHRCHRM1AKR1A1 | |
| Ether SCHEMBL9806062 | 0.80 | ALDH1A1 (0.44) | TP53ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702891-A | Double-component self-skinning polyurethane foam material and preparation method and application thereof | 江苏长能节能新材料科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118546643-A | Power battery PACK sealant, preparation method and application thereof | 江苏长顺高分子材料研究院有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-116836671-A | Enclosed polyurethane automobile roof adhesive, preparation method and application thereof | 江苏长顺高分子材料研究院有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-111902122-A | Use of a dry film in the topical application of a cosmetic product | 豪华轿车生物应用工业公司 | 2020-11-06 | — | — | CN | claimed |
| EP-2681176-B1 | PRODUCT INTENDED TO BE ADDED TO CROP IRRIGATION WATER | SPCM SA (FR) | 2016-12-28 | — | — | EP | claimed |
| US-20130340333-A1 | PRODUCT INTENDED TO BE ADDED TO CROP IRRIGATION WATER | S.P.C.M. SA (FR) | 2013-12-26 | — | — | US | claimed |
| US-20070264209-A1 | Soluble containers for self-tanning formulations | MERCK PATENT GMBH (DE) | 2007-11-15 | — | — | US | claimed |
| CN-1330661-C | Derivatives of monosaccharides for drug discovery | ALCHEMIA PTY CO LTD (AU) | 2007-08-08 | — | — | CN | claimed |
| US-20060167237-A1 | Derivatives of monosaccharides for drug discovery | ALCHEMIA LIMITED (AU) | 2006-07-27 | — | — | US | claimed |
| US-20060128592-A1 | Cosmetic effervescent cleansing pillow with water soluble or dispersible packet | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2006-06-15 | — | — | US | claimed |
| US-6509072-B2 | Multi-layer film with periodic barrier coating and methods of making and using such film | MONOSOL L.L.C. | 2003-01-21 | — | — | US | claimed |
| US-6484879-B2 | Water soluble packaging system and method | SYNGENTA CROP PROTECTION, INC. | 2002-11-26 | — | — | US | claimed |
| US-20020006485-A1 | MULTI-LAYER FILM WITH PERIODIC BARRIER COATING AND METHODS OF MAKING AND USING SUCH FILM | MONOSOL L.L.C. | 2002-01-17 | — | — | US | claimed |
| US-20010054567-A1 | WATER SOLUBLE PACKAGING SYSTEM, FILM AND METHOD | MONOSOL, LLC | 2001-12-27 | — | — | US | claimed |
| WO-2000064667-A1 | MULTI-LAYER FILM WITH PERIODIC BARRIER COATING AND METHODS OF MAKING AND USING SUCH FILM | CHRIS-CRAFT INDUSTRIAL PRODUCTS, INC. (US) | 2000-11-02 | — | — | WO | claimed |
| EP-0892744-B1 | WATER SOLUBLE BAG PACKAGING SYSTEM AND METHOD FOR PACKAGING | NOVARTIS AG (CH) | 2000-06-07 | — | — | EP | claimed |
| EP-0892744-A1 | WATER SOLUBLE BAG PACKAGING SYSTEM AND METHOD FOR PACKAGING | Novartis AG (CH) | 1999-01-27 | — | — | EP | claimed |
| WO-1998045185-A1 | WATER SOLUBLE PACKAGING SYSTEM, FILM AND METHOD | NOVARTIS AG (CH) | 1998-10-15 | — | — | WO | claimed |
| WO-1997037903-A1 | WATER SOLUBLE BAG PACKAGING SYSTEM AND METHOD FOR PACKAGING | NOVARTIS AG (CH) | 1997-10-16 | — | — | WO | claimed |
| US-5662735-A | Chemical solution for detecting counterfeit paper currency | PIFFERI PIERGIORGIO (IT) | 1997-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167237-A1 | Derivatives of monosaccharides for drug discovery | FBP1, UGGT1, FUT6 | CHRM1 4609/4885HTR2A 4615/4885HRH1 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.