Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.54 |
| ▸ | PDE4A | P27815 | 16/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724780 | 0.82 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL19459388 | 0.82 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7420740 | 0.73 | PDE4A (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7416733 | 0.70 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6323001 | 0.70 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6322447 | 0.70 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6322995 | 0.70 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7360492 | 0.69 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7919785 | 0.69 | PDE4A (0.50) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL16774566 | 0.69 | PDE4A (0.72) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609064-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | Neonc Technologies Inc. (US) | 2013-07-03 | — | — | EP | claimed |
| WO-2012027693-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | NEONC TECHNOLOGIES INC. (US) | 2012-03-01 | — | — | WO | claimed |
| EP-2609064-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | Neonc Technologies Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027693-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | NEONC TECHNOLOGIES INC. (US) | 2012-03-01 | — | — | WO | disclosed |