SCHEMBL724780

SCHEMBL724780

C=C(C)C1(c2ccc(OC)c(OC3CCCC3)c2)CC(=O)N(C(=O)OCC2=CCCCC2)C1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 19/20 0.47
PDE4A P27815 17/20 0.47
PDE4C Q08493 17/20 0.47
PDE4D Q08499 17/20 0.47
SLC5A7 Q9GZV3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19459388 1.00 PDE4B (0.47) PDE4BPDE4APDE4CPDE4DSLC5A7
SCHEMBL726264 0.82 PDE4B (0.54) PDE4BPDE4APDE4CPDE4D
SCHEMBL724779 0.68 PDE4A (0.51) PDE4BPDE4APDE4CPDE4D
SCHEMBL10081725 0.68 PDE4A (0.51) PDE4BPDE4APDE4CPDE4D
SCHEMBL7172357 0.66 PDE4B (0.62) PDE4BPDE4APDE4CPDE4D
SCHEMBL17339718 0.66 PDE4A (0.53) PDE4BPDE4APDE4CPDE4D
SCHEMBL7416733 0.65 PDE4B (1.00) PDE4BPDE4APDE4CPDE4D
SCHEMBL28546663 0.64 PDE4A (0.52) PDE4BPDE4APDE4CPDE4D
SCHEMBL7420740 0.63 PDE4A (0.66) PDE4BPDE4APDE4CPDE4D
SCHEMBL7191163 0.62 PDE4B (0.79) PDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016800-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2024-01-18 US claimed
US-20230405125-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL Neonc Technologies, Inc. 2023-12-21 US claimed
US-20220054481-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2022-02-24 US claimed
US-11147809-B2 Methods of treating neurofibromatosis with perillyl alcohol Neonc Technologies, Inc. (US) 2021-10-19 US claimed
US-11077104-B2 Pharmaceutical compositions comprising POH derivatives Neonc Technologies, Inc. (US) 2021-08-03 US claimed
US-11013804-B2 Pharmaceutical compositions comprising POH derivatives NeOncTechnologies, Inc. (US) 2021-05-25 US claimed
US-20200078462-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2020-03-12 US claimed
US-20190167669-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2019-06-06 US claimed
EP-3244930-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2017-11-22 EP claimed
US-20170297985-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL NEONC TECH INC (US) 2017-10-19 US claimed
US-20170128578-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. 2017-05-11 US claimed
US-9499461-B2 Pharmaceutical compositions comprising POH derivatives Neonc Technologies, Inc. (US) 2016-11-22 US claimed
EP-2609064-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING DERIVATIVES OF PERILLYL ALCOHOL NEONC TECHNOLOGIES INC (US) 2016-09-28 EP claimed
WO-2016115147-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2016-07-21 WO claimed
US-20160038600-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NATIONAL INSTITUTES OF HEALTH 2016-02-11 US claimed
EP-2898883-A1 Pharmaceutical compositions comprising perillyl alcohol carbamates Neonc Technologies Inc. (US) 2015-07-29 EP claimed
US-20130210877-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2013-08-15 US claimed
EP-2609064-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2013-07-03 EP claimed
WO-2012027693-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2012-03-01 WO claimed
US-20240197891-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-06-20 US disclosed
EP-4323070-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-02-21 EP disclosed
US-20240016800-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2024-01-18 US disclosed
US-20230405125-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL Neonc Technologies, Inc. 2023-12-21 US disclosed
US-11786521-B2 Methods of treating neurofibromatosis with perillyl alcohol UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-10-17 US disclosed
EP-4243794-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL Neonc Technologies, Inc. (US) 2023-09-20 EP disclosed
US-20230145207-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE UNIVERSITY OF SOUTHERN CALIFORNIA 2023-05-11 US disclosed
US-11559508-B2 Pharmaceutical compositions comprising POH derivatives and methods of use Neonc Technologies, Inc. (US) 2023-01-24 US disclosed
WO-2022104041-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL Neonc Technologies, Inc. (US) 2022-05-19 WO disclosed
US-20220133712-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2022-05-05 US disclosed
US-20220054481-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2022-02-24 US disclosed
US-11147809-B2 Methods of treating neurofibromatosis with perillyl alcohol Neonc Technologies, Inc. (US) 2021-10-19 US disclosed
US-20210283127-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2021-09-16 US disclosed
US-20210244820-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2021-08-12 US disclosed
US-11077104-B2 Pharmaceutical compositions comprising POH derivatives Neonc Technologies, Inc. (US) 2021-08-03 US disclosed
US-11013804-B2 Pharmaceutical compositions comprising POH derivatives NeOncTechnologies, Inc. (US) 2021-05-25 US disclosed
EP-3806838-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies, Inc. (US) 2021-04-21 EP disclosed
WO-2021061752-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies, Inc. (US) 2021-04-01 WO disclosed
US-20200237697-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE UNIVERSITY OF SOUTHERN CALIFORNIA 2020-07-30 US disclosed
EP-3685835-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies, Inc. (US) 2020-07-29 EP disclosed
US-20200230132-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE NATIONAL INSTITUTES OF HEALTH 2020-07-23 US disclosed
US-20200078462-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2020-03-12 US disclosed
US-20200078355-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies, Inc. 2020-03-12 US disclosed
US-20190275031-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2019-09-12 US disclosed
US-20190167669-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2019-06-06 US disclosed
US-20190054082-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE NATIONAL INSTITUTES OF HEALTH 2019-02-21 US disclosed
WO-2019014420-A1 COMPOSITIONS AND METHODS OF DECREASING MEDICATION ERRORS AZHC, LLC (US) 2019-01-17 WO disclosed
US-10092562-B2 Pharmaceutical compositions comprising POH derivatives Neonc Technologies, Inc. (US) 2018-10-09 US disclosed
US-9913838-B2 Methods of treating cancer using compositions comprising perillyl alcohol derivative Neonc Technologies, Inc. (US) 2018-03-13 US disclosed
US-20170369408-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC 2017-12-28 US disclosed
EP-3244930-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2017-11-22 EP disclosed
EP-3244930-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2017-11-22 EP disclosed
US-20170297985-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL NEONC TECH INC (US) 2017-10-19 US disclosed
EP-3173080-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2017-05-31 EP disclosed
US-9663428-B2 Pharmaceutical compositions comprising POH derivatives NEONC TECHNOLOGIES INC. (US) 2017-05-30 US disclosed
US-20170128578-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. 2017-05-11 US disclosed
US-20170119758-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2017-05-04 US disclosed
US-9580372-B2 Pharmaceutical compositions comprising POH derivatives NEONC TECHNOLOGIES INC. (US) 2017-02-28 US disclosed
EP-2898883-B1 Pharmaceutical compositions comprising perillyl alcohol carbamates NEONC TECHNOLOGIES INC (US) 2016-11-23 EP disclosed
US-9499461-B2 Pharmaceutical compositions comprising POH derivatives Neonc Technologies, Inc. (US) 2016-11-22 US disclosed
EP-2883543-B1 Pharmaceutical compositions comprising perillyl alcohol carbamates NEONC TECHNOLOGIES INC (US) 2016-11-16 EP disclosed
EP-2609064-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING DERIVATIVES OF PERILLYL ALCOHOL NEONC TECHNOLOGIES INC (US) 2016-09-28 EP disclosed
US-20160243114-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE UNIVERSITY OF SOUTHERN CALIFORNIA 2016-08-25 US disclosed
WO-2016115147-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2016-07-21 WO disclosed
WO-2016115147-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2016-07-21 WO disclosed
US-20160038600-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NATIONAL INSTITUTES OF HEALTH 2016-02-11 US disclosed
US-20160039731-A1 Pharmaceutical Compositions Comprising Deuterium-Enriched Perillyl Alcohol, Iso-Perillyl Alcohol and Derivatives Thereof NEONC TECHNOLOGIES INC 2016-02-11 US disclosed
EP-2898883-A1 Pharmaceutical compositions comprising perillyl alcohol carbamates Neonc Technologies Inc. (US) 2015-07-29 EP disclosed
EP-2883543-A1 Pharmaceutical compositions comprising perillyl alcohol carbamates Neonc Technologies Inc. (US) 2015-06-17 EP disclosed
WO-2015054333-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE Neonc Technologies, Inc. (US) 2015-04-16 WO disclosed
US-8916545-B2 Pharmaceutical compositions comprising POH derivatives NEONC TECHNOLOGIES INC. (US) 2014-12-23 US disclosed
US-20140364472-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2014-12-11 US disclosed
US-20140364471-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA 2014-12-11 US disclosed
US-20130210877-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2013-08-15 US disclosed
US-20130203828-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEO ONCOLOGY INC. (US) 2013-08-08 US disclosed
EP-2609064-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES Neonc Technologies Inc. (US) 2013-07-03 EP disclosed
WO-2012027693-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2012-03-01 WO disclosed
WO-2012027693-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES NEONC TECHNOLOGIES INC. (US) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (32 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133712-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20130203828-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20230145207-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE ACADVL, CPT1A, ADH5 PDE4B 1618/4885PDE4A 1590/4885PDE4C 1567/4885
US-20200230132-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE POLH, PLIN3, POLE3 PDE4B 2155/4885PDE4A 1973/4885PDE4C 2458/4885
US-20190054082-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE PLIN3, CHAT, PLIN5 PDE4B 1805/4885PDE4A 2234/4885PDE4C 2082/4885
US-20160038600-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PDE3A, PDE3B, PDE5A PDE4B 15/4885PDE4A 10/4885PDE4C 21/4885
US-20190275031-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20240197891-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, PLIN1 PDE4B 2553/4885PDE4A 2601/4885PDE4C 2817/4885
US-20170128578-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20220054481-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL PMP22, CHAT, REL PDE4B 1540/4885PDE4A 874/4885PDE4C 1374/4885
US-20190167669-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL PMP22, CHAT, REL PDE4B 1540/4885PDE4A 874/4885PDE4C 1374/4885
US-11147809-B2 Methods of treating neurofibromatosis with perillyl alcohol PMP22, CHAT, REL PDE4B 1540/4885PDE4A 874/4885PDE4C 1374/4885
US-20170369408-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20170297985-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL PMP22, REL, CHAT PDE4B 1843/4885PDE4A 1125/4885PDE4C 1637/4885
US-20160243114-A1 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE POLH, TOP2A, PLIN3 PDE4B 2303/4885PDE4A 2137/4885PDE4C 2544/4885
US-20200078355-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20160039731-A1 Pharmaceutical Compositions Comprising Deuterium-Enriched Perillyl Alcohol, Iso-Perillyl Alcohol and Derivatives Thereof ADH1C, ADH1A, ADH5 PDE4B 1150/4885PDE4A 1167/4885PDE4C 1029/4885
US-11077104-B2 Pharmaceutical compositions comprising POH derivatives PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20240016800-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL PMP22, CHAT, REL PDE4B 1540/4885PDE4A 874/4885PDE4C 1374/4885
US-20210283127-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-11786521-B2 Methods of treating neurofibromatosis with perillyl alcohol PMP22, CHAT, REL PDE4B 1540/4885PDE4A 874/4885PDE4C 1374/4885
US-20170119758-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1472/4885PDE4A 1478/4885PDE4C 1501/4885
US-20140364472-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-10092562-B2 Pharmaceutical compositions comprising POH derivatives PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885
US-20140364471-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1472/4885PDE4A 1478/4885PDE4C 1501/4885
US-20210244820-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, NR1H3 PDE4B 1642/4885PDE4A 1665/4885PDE4C 2062/4885
US-11559508-B2 Pharmaceutical compositions comprising POH derivatives and methods of use ACADVL, CPT1A, ADH5 PDE4B 1618/4885PDE4A 1590/4885PDE4C 1567/4885
US-20230405125-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL IDH3A, IDH1, IDH3B PDE4B 4120/4885PDE4A 3894/4885PDE4C 4407/4885
US-20200237697-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE ACADVL, CPT1A, ADH5 PDE4B 1618/4885PDE4A 1590/4885PDE4C 1567/4885
US-20200078462-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PDE3A, PDE3B, PDE5A PDE4B 15/4885PDE4A 10/4885PDE4C 21/4885
US-11013804-B2 Pharmaceutical compositions comprising POH derivatives PDE3A, PDE3B, PDE5A PDE4B 15/4885PDE4A 10/4885PDE4C 21/4885
US-20130210877-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PLIN3, PLIN5, DOHH PDE4B 1525/4885PDE4A 1501/4885PDE4C 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.