Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268893 | 0.77 | MAPK10 (0.46) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL7264106 | 0.76 | KMT2A (0.44) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL7271120 | 0.73 | RAB9A (0.58) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL7268866 | 0.73 | BACE1 (0.51) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL7264088 | 0.72 | MEN1 (0.44) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL221242 | 0.72 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL29391624 | 0.72 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL2037194 | 0.72 | MAPT (0.52) | KMT2AMEN1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL6574416 | 0.70 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERL3MBTL1 | |
| SCHEMBL11133606 | 0.70 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |