Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262715 | 0.80 | KDR (0.37) | MEN1KMT2AALDH1A1L3MBTL1KDR | |
| SCHEMBL7264088 | 0.79 | MEN1 (0.44) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL7271141 | 0.77 | RAB9A (0.37) | MEN1KMT2AALDH1A1KDRNPC1 | |
| SCHEMBL7262734 | 0.77 | KMT2A (0.48) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL7264106 | 0.76 | KMT2A (0.44) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL7271120 | 0.74 | RAB9A (0.58) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL17817052 | 0.74 | MAPT (0.53) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL221242 | 0.70 | KMT2A (0.76) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL29391624 | 0.70 | KMT2A (0.76) | MAPK10MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL12373361 | 0.68 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1KDRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |