Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264106 | 0.79 | KMT2A (0.44) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL7262734 | 0.73 | KMT2A (0.48) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL7271120 | 0.71 | RAB9A (0.58) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL987908 | 0.71 | BACE1 (1.00) | BACE1ALDH1A1MAOAMAOBMAPT | |
| SCHEMBL7264088 | 0.70 | MEN1 (0.44) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL29391624 | 0.67 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL221242 | 0.67 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL904463 | 0.65 | MEN1 (0.55) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL7268893 | 0.65 | MAPK10 (0.46) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL6574416 | 0.65 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |