Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208037 | 0.82 | TAAR1 (0.50) | NPC1RAB9ASMN1; SMN2TAAR1CA1 | |
| SCHEMBL5632849 | 0.81 | MEN1 (0.55) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3217657 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2TAAR1CA1 | |
| SCHEMBL12601569 | 0.78 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2TAAR1CA1 | |
| SCHEMBL2840589 | 0.78 | CA1 (0.48) | NPC1RAB9ASMN1; SMN2TAAR1CA1 | |
| SCHEMBL6564813 | 0.78 | TDP1 (0.56) | SMN1; SMN2TAAR1CA1CA2LMNA | |
| SCHEMBL10689007 | 0.77 | CYP19A1 (0.48) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL4600838 | 0.77 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2TAAR1CA1 | |
| SCHEMBL4780885 | 0.76 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL2880966 | 0.76 | TAAR1 (0.50) | NPC1RAB9ASMN1; SMN2TAAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |