SCHEMBL3208037

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7263003	0.82	NPC1 (0.53)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL14380628	0.81	MEN1 (0.55)	CA1CA2CA12KDM4EL3MBTL1
	SCHEMBL6564813	0.78	TDP1 (0.56)	TAAR1SMN1; SMN2CA1CA2KDM4E
	SCHEMBL12601569	0.78	SMN1; SMN2 (0.45)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL2840589	0.78	CA1 (0.48)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL10689007	0.77	CYP19A1 (0.48)	NPC1RAB9ASMN1; SMN2CA1CA2
	SCHEMBL4600838	0.77	NPC1 (0.48)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL3217657	0.76	NPC1 (0.50)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL4067422	0.76	TAAR1 (0.55)	TAAR1NPC1RAB9ASMN1; SMN2CA1
	SCHEMBL8883079	0.74	ALDH1A1 (0.56)	TAAR1NPC1RAB9APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.