Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263969 | 0.88 | ADA (0.40) | ADA | |
| SCHEMBL7263912 | 0.87 | ADA (0.39) | SCN9AADA | |
| SCHEMBL7263295 | 0.86 | ADA (0.39) | SCN9AADA | |
| SCHEMBL7259594 | 0.81 | NPC1 (0.40) | — | |
| SCHEMBL7258938 | 0.80 | KDM4E (0.42) | — | |
| SCHEMBL7263288 | 0.80 | RAB9A (0.47) | ADAACACB | |
| SCHEMBL7453006 | 0.76 | NPC1 (0.40) | ADA | |
| SCHEMBL7258813 | 0.76 | POLB (0.38) | — | |
| SCHEMBL7259217 | 0.75 | SMN1; SMN2 (0.41) | ACACB | |
| SCHEMBL7259234 | 0.74 | FFAR4 (0.41) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |