Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263969 | 0.90 | ADA (0.40) | ADAMAPTRECQL | |
| SCHEMBL7263912 | 0.89 | ADA (0.39) | ADAMAPTHTTPDE3BPDE3A | |
| SCHEMBL7263100 | 0.86 | SCN9A (0.44) | ADASCN9A | |
| SCHEMBL7259876 | 0.85 | RAB9A (0.32) | ADACYP3A4CYP2D6LMNAMEN1 | |
| SCHEMBL7259594 | 0.83 | NPC1 (0.40) | CYP3A4LMNAMEN1KMT2ARXFP1 | |
| SCHEMBL7258938 | 0.82 | KDM4E (0.42) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7263288 | 0.82 | RAB9A (0.47) | ADACYP2D6MAPTHTTSMN1; SMN2 | |
| SCHEMBL7453006 | 0.78 | NPC1 (0.40) | ADAMEN1KMT2AMAPTRECQL | |
| SCHEMBL7258813 | 0.78 | POLB (0.38) | LMNAMAPTHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7263079 | 0.78 | TP53 (0.46) | SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |