Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263594 | 0.87 | RAB9A (0.43) | RAB9ASMN1; SMN2KDM4ENPC1MAPK1 | |
| SCHEMBL7263969 | 0.83 | ADA (0.40) | KDM4EPPARGPPARAALDH1A1ALOX5 | |
| SCHEMBL7263912 | 0.83 | ADA (0.39) | PPARGPPARAHTTADAMAPT | |
| SCHEMBL7259594 | 0.82 | NPC1 (0.40) | RAB9ANPC1MAPK1PPARGPPARA | |
| SCHEMBL7263295 | 0.82 | ADA (0.39) | SMN1; SMN2HTTADAMAPTCYP2D6 | |
| SCHEMBL7258938 | 0.81 | KDM4E (0.42) | SMN1; SMN2KDM4EALDH1A1MCL1POLB | |
| SCHEMBL7263100 | 0.80 | SCN9A (0.44) | ADAACACB | |
| SCHEMBL7263079 | 0.79 | TP53 (0.46) | RAB9ASMN1; SMN2NPC1MAPK1ALDH1A1 | |
| SCHEMBL7263879 | 0.78 | MAPT (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL7259234 | 0.77 | FFAR4 (0.41) | RAB9ASMN1; SMN2NPC1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |