Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536003 | 0.91 | C3AR1 (0.50) | HPGDACEPTPN1C3AR1CA2 | |
| SCHEMBL25561171 | 0.85 | HPGD (0.48) | HPGDCTSLMEN1HTTKMT2A | |
| SCHEMBL13360851 | 0.84 | PTPN1 (0.48) | PTPN1CA2CA1MEN1HTT | |
| SCHEMBL10656249 | 0.83 | CTSL (0.49) | HPGDCTSLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28409793 | 0.82 | NAALAD2 (0.45) | HPGDACEPTPN1C3AR1CA2 | |
| SCHEMBL9829488 | 0.81 | SLC1A2 (0.53) | HPGDACEPTPN1C3AR1CA2 | |
| SCHEMBL9829492 | 0.81 | SLC1A2 (0.53) | HPGDACEPTPN1C3AR1CA2 | |
| SCHEMBL13776441 | 0.81 | CAPN1 (0.49) | HPGDMEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL2330376 | 0.80 | CTRB1 (0.51) | HPGDACEPTPN1C3AR1CA2 | |
| SCHEMBL10404280 | 0.80 | C3AR1 (0.51) | HPGDACEPTPN1C3AR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220529-B | A kind of preparation method and Pharmaceutical composition of chiral proglumide | 成都译山生物科技有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-107427699-A | For treating the KDM1A inhibitor of disease | 伊美格生物科学公司 | 2017-12-01 | — | — | CN | disclosed |
| US-6558633-B1 | Chemical reaction apparatus and methods | ISIS PHARMACEUTICALS, INC. | 2003-05-06 | — | — | US | disclosed |
| US-20010028866-A1 | Chemical synthesis apparatus employing a droplet generator | ISIS PHARMACEUTICALS, INC. | 2001-10-11 | — | — | US | disclosed |
| US-6277334-B1 | TO PREPARE OLIGOMERS AND LIBRARIES OF CHEMICAL SPECIES. | ISIS PHARMACEUTICALS, INC. | 2001-08-21 | — | — | US | disclosed |
| US-5925732-A | CHEMICAL DROPLET GENERATION AND DIRECTION TECHNIQUES ARE EMPLOYED TO PREPARE OLIGOMERS, POLYPEPTIDES, AND NUCLEIC ACIDS, AND LIBRARIES OF CHEMICAL SPECIES | ISIS PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |