Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 9/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829492 | 1.00 | SLC1A2 (0.53) | SLC1A2ACECA2CA1PTPN1 | |
| SCHEMBL16151168 | 0.88 | C3AR1 (0.52) | ACECA2CA1PTPN1C3AR1 | |
| SCHEMBL16151169 | 0.88 | C3AR1 (0.52) | ACECA2CA1PTPN1C3AR1 | |
| SCHEMBL2791574 | 0.85 | CA2 (0.66) | SLC1A2ACECA2CA1PTPN1 | |
| SCHEMBL9943491 | 0.85 | CA2 (0.66) | SLC1A2ACECA2CA1PTPN1 | |
| SCHEMBL2792747 | 0.85 | CA2 (0.66) | SLC1A2ACECA2CA1PTPN1 | |
| SCHEMBL698067 | 0.84 | CA2 (0.67) | CA2CA1HPGDTDP1LMNA | |
| SCHEMBL715646 | 0.84 | CA2 (0.67) | CA2CA1HPGDTDP1LMNA | |
| SCHEMBL2330374 | 0.84 | CTRB1 (0.51) | SLC1A2ACECA2CA1PTPN1 | |
| SCHEMBL2330376 | 0.84 | CTRB1 (0.51) | SLC1A2ACECA2CA1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |