SCHEMBL7263146

SCHEMBL7263146

CCN1c2ccccc2N(CC)c2cc(-c3ccccc3)c(-c3ccccc3)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 9/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
TP53 P04637 1/20 0.38
HTT P42858 1/20 0.38
BACE1 P56817 1/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
MGLL Q99685 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
MPI P34949 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2877910 0.80
SCHEMBL29699888 0.80 POLB (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL474136 0.80 POLB (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL5072094 0.76 MAPT (0.44) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL5069383 0.74 MAOA (0.43) ALDH1A1BACE1MGLLHSD17B10HTR1A
SCHEMBL9917544 0.72 CYP2A6 (0.43) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL21076086 0.71 ELANE (0.42) MEN1KMT2AALDH1A1MAPTMGLL
SCHEMBL13066273 0.68 CYP1A2 (0.34) KMT2AALDH1A1MAPTKDM4ENR1H2
SCHEMBL10133970 0.67 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL23890049 0.67 ALDH1A1 (0.49) MEN1KMT2AALDH1A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6661559-B2 Transparent substrate having an electrically conductive material; redox electroactive compounds; colorimetric analysis GENTEX CORPORATION 2003-12-09 US disclosed
US-20020051278-A1 Electrochromic media for producing a preselected color and devices comprising same BYKER HARLAN J (US) 2002-05-02 US disclosed
US-6288825-B1 Electrochromic media for producing a preselected color and devices comprising same GENTEX CORPORATION 2001-09-11 US disclosed
US-6141137-A Electrochromic media for producing a preselected color GENTEX CORPORATION (US) 2000-10-31 US disclosed