Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263161 | 1.00 | MGLL (0.47) | MGLLHPGDALDH1A1MAPTTP53 | |
| SCHEMBL7263159 | 1.00 | MGLL (0.47) | MGLLHPGDALDH1A1MAPTTP53 | |
| Citric Acid SCHEMBL7977599 | 0.89 | MGLL (0.39) | MGLLHPGDALDH1A1TP53HTT | |
| Citric Acid SCHEMBL7989107 | 0.89 | MGLL (0.39) | MGLLHPGDALDH1A1TP53HTT | |
| Citric Acid SCHEMBL7977602 | 0.89 | MGLL (0.39) | MGLLHPGDALDH1A1TP53HTT | |
| SCHEMBL7268696 | 0.85 | HPGD (0.52) | MGLLHPGDALDH1A1TP53HTT | |
| SCHEMBL7270759 | 0.85 | HPGD (0.52) | MGLLHPGDALDH1A1TP53HTT | |
| SCHEMBL7268720 | 0.77 | OPRD1 (0.48) | HPGDALDH1A1MAPT | |
| SCHEMBL7270013 | 0.77 | OPRD1 (0.48) | HPGDALDH1A1MAPT | |
| SCHEMBL7268714 | 0.77 | OPRD1 (0.48) | HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873330-B1 | DIARYLALKENYLAMINE DERIVATIVES | GLAXOSMITHKLINE SPA (IT) | 2003-05-14 | — | — | EP | claimed |