Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668731 | 0.83 | MAPT (0.52) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL16254045 | 0.79 | MAPT (0.39) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL6271908 | 0.77 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL1071244 | 0.70 | MAPK1 (0.50) | MAPTNPSR1SMN1; SMN2MAPK1SIGMAR1 | |
| SCHEMBL4019885 | 0.70 | SLC18A3 (0.42) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL8811436 | 0.70 | MAPT (0.41) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL6622485 | 0.69 | CHRNB2 (0.43) | MAPTNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL12254378 | 0.69 | MAPK1 (0.49) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL23828167 | 0.67 | SLC18A3 (0.41) | MAPTNPSR1SMN1; SMN2MAPK1HTT | |
| SCHEMBL474882 | 0.67 | SIGMAR1 (0.52) | MAPTSMN1; SMN2MAPK1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1360007-A1 | METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES | Vir A/S (DK) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002066162-A1 | METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES | VIR A/S (DK) | 2002-08-29 | — | — | WO | disclosed |
| US-20020115224-A1 | Method for the preparation of optical (bio)chemical sensor devices | VIR A/S (DK) | 2002-08-22 | — | — | US | disclosed |