SCHEMBL474882

SCHEMBL474882

c1ccc(N2CN(c3ccccc3)CN(c3ccccc3)C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.52
LMNA P02545 2/20 0.52
HTR3E A5X5Y0 1/20 0.52
HTR3B O95264 1/20 0.52
ADRB1 P08588 1/20 0.52
HTR3A P46098 1/20 0.52
HTR3D Q70Z44 1/20 0.52
HTR3C Q8WXA8 1/20 0.52
CHRNA7 P36544 3/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
CHRNB2 P17787 1/20 0.48
NFKB1 P19838 1/20 0.48
MAPK1 P28482 1/20 0.48
CHRNA3 P32297 1/20 0.48
CHRNA4 P43681 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006036 0.88 LMNA (0.54) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL14859797 0.87 LMNA (0.43) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL28644066 0.85 LMNA (0.46) SIGMAR1LMNAHTR3EHTR3BADRB1
Hydrochloric Acid SCHEMBL14334304 0.85 LMNA (0.52) SIGMAR1LMNAHTR3EHTR3BADRB1
Bromide SCHEMBL19272502 0.85 LMNA (0.52) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL28402413 0.84 ALDH1A1 (0.49) SIGMAR1LMNAALOX15MAPK1MEN1
SCHEMBL19315410 0.84 MAPT (0.49) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL10966975 0.84 MAPT (0.49) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL15987689 0.84 LMNA (0.41) SIGMAR1LMNAHTR3EHTR3BADRB1
SCHEMBL2046994 0.83 LMNA (0.50) SIGMAR1LMNAHTR3EHTR3BADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082209-A Cross-linking agent, preparation method thereof, cross-linked polymer and application 江苏上上电缆集团有限公司 2023-05-09 CN claimed
EP-3436429-B1 BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-06-16 EP claimed
CN-107356998-B Optical film and flexible device using the same 住友化学株式会社 2021-04-23 CN claimed
EP-2962991-B1 METHOD FOR PRODUCING CARBON MATERIAL NISSHINBO HOLDINGS INC (JP) 2019-09-18 EP claimed
EP-3436429-A1 BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION Dow Global Technologies, LLC (US) 2019-02-06 EP claimed
US-20190023652-A1 BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION DOW GLOBAL TECHNOLOGIES LLC 2019-01-24 US claimed
US-20170329062-A1 OPTICAL FILM AND FLEXIBLE DEVICE USING THE OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-16 US claimed
WO-2017172313-A1 BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-05 WO claimed
EP-1765756-B1 OLIGOMERIC DERIVATIVES OF SPIROBIFLUORENE, THEIR PREPARATION AND USE MERCK PATENT GMBH (DE) 2016-12-28 EP claimed
CN-105085910-A Intrinsically flame retardant bio-based benzoxazine resin and preparation method thereof NINGBO INST TECH ZHEJIANG UNIV 2015-11-25 CN claimed
US-8614357-B2 Oligomeric derivatives of spirobifluorene, their preparation and use MERCK PATENT GMBH (DE) 2013-12-24 US claimed
CN-101076508-B Spirobifluorene oligomerization derivative, its preparation and application MERCK PATENT GMBH 2011-05-04 CN claimed
US-20110054124-A1 POLYAMIC ACID RESIN COMPOSITION AND METHOD FOR FORMING POLYIMIDE RESIN INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-03-03 US claimed
US-20090234164-A1 Oligomeric derivatives of spirobifluorene, their preparation and use MERCK PATENT GMBH (DE) 2009-09-17 US claimed
CN-101076508-A Spirobifluorene oligomerization derivative, its preparation and application MERCK PATENT GMBH (DE) 2007-11-21 CN claimed
US-4028361-A Process for the purification of MDA THE UPJOHN COMPANY (US) 1977-06-07 US claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20250179351-A1 ORGANIC LIGHT-EMITTING MATERIAL CONTAINING TETRAPHENYLBENZENE, PREPARATION,AND APPLICATION SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2025-06-05 US disclosed
US-4028361-A Process for the purification of MDA THE UPJOHN COMPANY (US) 1977-06-07 US disclosed
US-3933831-A Perfluorinated tertiary amines PCR, INC. (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190023652-A1 BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION BCCIP, PAICS, MMAB SIGMAR1 4009/4885LMNA 3369/4885HTR3E 4356/4885
US-20090234164-A1 Oligomeric derivatives of spirobifluorene, their preparation and use NR3C2, NR0B2, NR0B1 SIGMAR1 44/4885LMNA 1216/4885HTR3E 2578/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 SIGMAR1 2882/4885LMNA 4529/4885HTR3E 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.