Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EYA2 | O00167 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262524 | 0.94 | MAPT (0.59) | ALDH1A1ABCC4MAPTLMNAL3MBTL1 | |
| SCHEMBL7262491 | 0.92 | MAPT (0.62) | ALDH1A1ABCC4MAPTLMNALPAR2 | |
| SCHEMBL7262031 | 0.92 | MAPT (0.62) | ALDH1A1ABCC4MAPTLMNALPAR2 | |
| SCHEMBL22322158 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL3118284 | 0.78 | LMNA (0.64) | ALDH1A1ABCC4MAPTLMNATSHR | |
| SCHEMBL12888853 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ABCC4MAPTLMNAL3MBTL1 | |
| SCHEMBL20467671 | 0.75 | MMP2 (0.40) | ALDH1A1ABCC4MAPTLMNATSHR | |
| SCHEMBL29088661 | 0.75 | MAPT (0.81) | ALDH1A1ABCC4MAPTLMNAL3MBTL1 | |
| SCHEMBL60128 | 0.75 | — | — | |
| SCHEMBL16289079 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ABCC4MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653087-B1 | Convergent synthesis of combinatorial library | THE SCRIPPS RESEARCH INSTITUTE | 2003-11-25 | — | — | US | disclosed |
| EP-0968423-A4 | CONVERGENT SYNTHESIS OF COMBINATORIAL LIBRARY | SCRIPPS RESEARCH INST (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-0968423-A1 | CONVERGENT SYNTHESIS OF COMBINATORIAL LIBRARY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998035231-A1 | CONVERGENT SYNTHESIS OF COMBINATORIAL LIBRARY | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-13 | — | — | WO | disclosed |