Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264106 | 0.80 | KMT2A (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL7264111 | 0.73 | RAB9A (0.36) | ALDH1A1MAPTSMN1; SMN2ACHE | |
| SCHEMBL7262715 | 0.73 | KDR (0.37) | ALDH1A1MEN1GUCY1B2MAPTGUCY1A2 | |
| SCHEMBL7262766 | 0.67 | MAPT (0.62) | ALDH1A1MEN1GUCY1B2MAPTGUCY1A2 | |
| SCHEMBL21463 | 0.66 | MAPT (0.41) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28093506 | 0.63 | MAPT (0.39) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2174053 | 0.63 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7262729 | 0.60 | IDO1 (0.60) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| Duroquinone SCHEMBL11408085 | 0.60 | DDAH1 (0.36) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27311239 | 0.57 | SLC2A1 (0.50) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |