Biphenyl

Biphenyl

SCHEMBL7263262

Cc1ccc(S)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
ALDH1A1 P00352 4/20 0.47
RAB9A P51151 5/20 0.45
NPC1 O15118 4/20 0.45
HPGD P15428 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
NFKB1 P19838 2/20 0.45
NFKB2 Q00653 2/20 0.45
RELA Q04206 2/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC2A1 P11166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27530460 0.91 ACHE (0.42) ACHELMNATSHRALOX12ALDH1A1
Toluene SCHEMBL2716936 0.90 LMNA (0.58) ACHELMNATSHRALOX12ALDH1A1
Toluene SCHEMBL10802247 0.89 ACHE (0.65) ACHELMNATSHRALOX12ALDH1A1
Toluene SCHEMBL28207707 0.89 ACHE (0.65) ACHELMNATSHRALOX12ALDH1A1
Benzenethiol SCHEMBL6553066 0.89 ACHE (0.56) ACHELMNATSHRALOX12ALDH1A1
SCHEMBL12960035 0.86 ACHE (0.50) ACHELMNATSHRALOX12ALDH1A1
Toluene SCHEMBL10710211 0.86 ACHE (0.69) ACHELMNATSHRALOX12RAB9A
P-Xylene SCHEMBL29155380 0.86 ACHE (0.59) ACHELMNATSHRALOX12ALDH1A1
SCHEMBL862135 0.86 ACHE (0.50) ACHELMNATSHRALOX12ALDH1A1
Biphenyl SCHEMBL27571673 0.86 ALDH1A1 (0.64) LMNAALDH1A1RAB9ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656660-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-02 US disclosed
EP-1024406-A1 Resist composition WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 2000-08-02 EP disclosed