Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263602 | 0.86 | PPARG (0.41) | ADAPPARGPPARAALOX5ALDH1A1 | |
| SCHEMBL7259601 | 0.83 | ADA (0.44) | ADAPPARGPPARAALDH1A1RAB9A | |
| SCHEMBL7258942 | 0.82 | ADA (0.43) | ADAALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7263915 | 0.82 | ADA (0.48) | ADAPPARGPPARA | |
| SCHEMBL7263299 | 0.82 | ADA (0.48) | ADAPPARGPPARASMN1; SMN2MAPK1 | |
| SCHEMBL7263103 | 0.79 | ADA (0.46) | ADAPPARGPPARAALDH1A1KDM4E | |
| SCHEMBL7263874 | 0.79 | ADA (0.43) | ADAALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL7263886 | 0.77 | ADA (0.41) | ADAALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5670994 | 0.76 | ADA (0.80) | ADAPPARGPPARAALOX5ALDH1A1 | |
| SCHEMBL7448841 | 0.76 | ALDH1A1 (0.42) | ADAALDH1A1MCL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |