Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ADA | P00813 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453012 | 0.91 | ADA (0.48) | PPARGPPARAADAALOX5RAB9A | |
| SCHEMBL7258926 | 0.86 | MRGPRX4 (0.44) | PPARGPPARAADA | |
| SCHEMBL7263294 | 0.86 | ADA (0.47) | PPARGPPARAADAMCL1ALOX5 | |
| SCHEMBL7258752 | 0.85 | ATM (0.41) | PPARGPPARAADAALOX5KDM4E | |
| SCHEMBL7263300 | 0.83 | PDE10A (0.39) | ADACYP3A4MAPT | |
| SCHEMBL7264016 | 0.82 | MCHR1 (0.40) | ADAALOX5 | |
| SCHEMBL7259591 | 0.82 | LMNA (0.42) | ADAALDH1A1MAPTLMNA | |
| SCHEMBL7449954 | 0.80 | KMT2A (0.39) | MCL1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL5671007 | 0.79 | ADA (0.63) | PPARGPPARAADAMCL1ALOX5 | |
| SCHEMBL7448692 | 0.79 | ADA (0.38) | ADAALOX5KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |