Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263915 | 0.86 | ADA (0.48) | ADASCN9AFPR2PPARGPPARD | |
| SCHEMBL7263299 | 0.86 | ADA (0.48) | ADAMAPTPPARGPPARDPPARA | |
| SCHEMBL7259601 | 0.81 | ADA (0.44) | ADAALDH1A1MAPTPPARGPPARD | |
| SCHEMBL7258942 | 0.81 | ADA (0.43) | ADAALDH1A1KDM4E | |
| SCHEMBL7263294 | 0.79 | ADA (0.47) | ADAALDH1A1MAPTPPARGPPARA | |
| SCHEMBL5671864 | 0.77 | ADA (0.78) | ADA | |
| SCHEMBL7263874 | 0.75 | ADA (0.43) | ADAALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL7453012 | 0.74 | ADA (0.48) | ADAALDH1A1MAPTPPARGPPARD | |
| SCHEMBL7263100 | 0.73 | SCN9A (0.44) | ADASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL7258747 | 0.73 | ADA (0.39) | ADASCN9AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |