Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258595 | 0.91 | — | — | |
| SCHEMBL7264435 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7264499 | 0.80 | — | — | |
| SCHEMBL7263185 | 0.79 | — | — | |
| SCHEMBL8154174 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8154422 | 0.76 | — | — | |
| SCHEMBL5940600 | 0.74 | — | — | |
| SCHEMBL7253779 | 0.74 | — | — | |
| SCHEMBL8152565 | 0.73 | — | — | |
| SCHEMBL7257430 | 0.73 | NPC1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000664-A1 | URACIL DERIVATIVES AND THE USE THEREOF FOR TREATING BACTERIAL DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |