Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273272 | 0.90 | PREP (0.50) | RENACELMNAPREPCTRB1 | |
| SCHEMBL7265589 | 0.90 | PREP (0.50) | RENACELMNAPREPCTRB1 | |
| SCHEMBL7272969 | 0.86 | CMA1 (0.49) | RENACECMA1LMNAPREP | |
| SCHEMBL7271793 | 0.85 | ACE (0.56) | RENACECMA1LMNASMN1; SMN2 | |
| SCHEMBL7273277 | 0.84 | ACE (0.47) | RENACECMA1LMNAPREP | |
| SCHEMBL7273065 | 0.84 | ACE (0.52) | ACECMA1LMNAACE2 | |
| SCHEMBL10932183 | 0.84 | FKBP1A (0.56) | ACELMNAPREPACE2 | |
| SCHEMBL7264182 | 0.83 | ACE (0.56) | ACECMA1ACE2 | |
| SCHEMBL7263810 | 0.83 | ACE (0.52) | ACECMA1LMNAACE2 | |
| SCHEMBL7265461 | 0.83 | LMNA (0.53) | ACECMA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |