Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | CMA1 | P23946 | 5/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.47 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264182 | 0.92 | ACE (0.56) | ACECMA1ACE2OPRM1ELANE | |
| SCHEMBL7263810 | 0.92 | ACE (0.52) | ACECMA1CPA1CPA2CPA4 | |
| SCHEMBL7263953 | 0.88 | SLC6A2 (0.57) | ACECMA1ACE2OPRM1SLC6A2 | |
| Arginine SCHEMBL7270315 | 0.87 | EPHA2 (0.47) | ACECMA1OPRM1SLC6A2 | |
| SCHEMBL7273277 | 0.85 | ACE (0.47) | ACECMA1CPA1CPA2CPA4 | |
| SCHEMBL7263961 | 0.85 | ACE (0.48) | ACECMA1CPA1CPA2CPA4 | |
| SCHEMBL7263639 | 0.84 | REN (0.48) | ACECMA1ACE2LMNA | |
| SCHEMBL7264237 | 0.84 | ACE (0.61) | ACEACE2LMNA | |
| SCHEMBL7264225 | 0.84 | ACE (0.61) | ACEACE2LMNA | |
| SCHEMBL7271793 | 0.84 | ACE (0.56) | ACECMA1ACE2LMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |