Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264134 | 0.80 | ALDH1A1 (0.41) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL960053 | 0.78 | LMNA (0.44) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL9608839 | 0.78 | HCAR2 (0.62) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL3208200 | 0.78 | — | — | |
| SCHEMBL15921055 | 0.77 | ALDH1A1 (0.44) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL4297402 | 0.75 | — | — | |
| SCHEMBL4292895 | 0.74 | HCAR2 (0.42) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL24415622 | 0.74 | HDAC3 (0.36) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL26702857 | 0.74 | OGA (0.39) | HCAR2NPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL7264808 | 0.73 | POLB (0.44) | HCAR2NPC1SMN1; SMN2HPGDOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029231-A1 | NEMATICIDAL TRIFLUOROBUTENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-04-10 | — | — | WO | disclosed |