Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | OGA | O60502 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259530 | 0.80 | TP53 (0.43) | POLBALDH1A1KDM4EHPGDOGA | |
| SCHEMBL11650054 | 0.78 | USP2 (0.46) | POLBPKMALDH1A1KDM4ENPC1 | |
| SCHEMBL11956367 | 0.78 | HCAR2 (0.62) | POLBPKMALDH1A1KDM4ENPC1 | |
| SCHEMBL4292895 | 0.78 | HCAR2 (0.42) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL3208200 | 0.78 | — | — | |
| SCHEMBL18236191 | 0.77 | RAB9A (0.58) | POLBPKMALDH1A1KDM4ENPC1 | |
| SCHEMBL3401366 | 0.77 | NOS1 (0.42) | POLBPKMALDH1A1KDM4ENPC1 | |
| SCHEMBL294099 | 0.77 | POLB (0.41) | POLBPKMALDH1A1KDM4ENPC1 | |
| SCHEMBL4297402 | 0.75 | — | — | |
| SCHEMBL7264799 | 0.75 | RAB9A (0.45) | POLBALDH1A1KDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029231-A1 | NEMATICIDAL TRIFLUOROBUTENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-04-10 | — | — | WO | disclosed |