Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MVD | P53602 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925210 | 0.95 | ACE (0.53) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| SCHEMBL1000948 | 0.95 | ACE (0.53) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10976646 | 0.94 | ACE (0.52) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| SCHEMBL29843876 | 0.88 | ACE (0.42) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| SCHEMBL8352289 | 0.85 | MEN1 (0.49) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| SCHEMBL14979025 | 0.85 | MEN1 (0.49) | ACEHSD17B10MEN1ALDH1A1TSHR | |
| SCHEMBL2744394 | 0.84 | MEN1 (0.48) | ACEMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL14235217 | 0.84 | KLK5 (0.53) | ACEMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL6468703 | 0.84 | KLK5 (0.53) | ACEMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL3763934 | 0.84 | MEN1 (0.48) | ACEMEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |