Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 4/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352289 | 1.00 | MEN1 (0.49) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL21101551 | 0.90 | MEN1 (0.47) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL1000948 | 0.89 | ACE (0.53) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL1925210 | 0.89 | ACE (0.53) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL6468703 | 0.88 | KLK5 (0.53) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL3763934 | 0.88 | MEN1 (0.48) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL2744394 | 0.88 | MEN1 (0.48) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL14235217 | 0.88 | KLK5 (0.53) | MEN1ALDH1A1TSHRKMT2AFAP | |
| Hydrochloric Acid SCHEMBL10976646 | 0.88 | ACE (0.52) | MEN1ALDH1A1TSHRKMT2AFAP | |
| SCHEMBL13071552 | 0.87 | ALDH1A1 (0.47) | MEN1ALDH1A1TSHRKMT2AFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20140249073-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC (US) | 2014-09-04 | — | — | US | disclosed |
| US-8450529-B2 | Branched polyamines and formulations thereof for use in medical devices | COVIDIEN LP (US) | 2013-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249073-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | MEN1 4112/4885ALDH1A1 2541/4885TSHR 4423/4885 |
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | MEN1 4112/4885ALDH1A1 2541/4885TSHR 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.