Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746231 | 0.87 | TSHR (0.62) | TSHRTDP1CYP3A4ATMHCAR2 | |
| Acrylic Acid Ethyl Ester SCHEMBL11247075 | 0.86 | TSHR (0.69) | TSHRTDP1CYP3A4ATMHCAR2 | |
| SCHEMBL6133463 | 0.85 | TSHR (0.64) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| Acrylic Acid SCHEMBL11282590 | 0.84 | TSHR (0.71) | TSHRTDP1CYP3A4ATMHCAR2 | |
| Acrylic Acid SCHEMBL516623 | 0.84 | TSHR (0.74) | TSHRTDP1CYP3A4ATMHCAR2 | |
| Acrylic Acid Ethyl Ester SCHEMBL11247076 | 0.84 | TSHR (0.55) | TSHRTDP1CYP3A4ATMHCAR2 | |
| Ethyl Fumarate SCHEMBL11211795 | 0.83 | TSHR (0.76) | TSHRTDP1CYP3A4ATMHCAR2 | |
| Ethyl Fumarate SCHEMBL11211796 | 0.83 | TSHR (0.76) | TSHRTDP1CYP3A4ATMHCAR2 | |
| SCHEMBL560438 | 0.83 | TSHR (0.81) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL9422195 | 0.83 | TSHR (0.62) | TSHRTDP1CYP3A4ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238025-B2 | Transdermal preparation comprising a ropinirole derivative | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2438917-B1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-20120052113-A1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20080226697-A1 | Patch for External Use with Elevated Content of Absorption Promoter in Pressure-Sensitive Adhesive Base | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052113-A1 | TRANSDERMAL PREPARATION | HTR3D, HTR5A, HTR1E | TSHR 3182/4885TDP1 2612/4885CYP3A4 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.