Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629539 | 0.85 | CARM1 (0.47) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL9281673 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL4482337 | 0.80 | CARM1 (0.55) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL19715624 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL24926944 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| Dibemethine SCHEMBL10542007 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| Dibemethine SCHEMBL276863 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL23032284 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL7270829 | 0.77 | CARM1 (0.47) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL25237515 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRCARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895517-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | claimed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | claimed |
| EP-2706073-A1 | Two-component polyurethane composition | Sika Technology AG (CH) | 2014-03-12 | — | — | EP | claimed |
| WO-2013171200-A1 | REACTIVE POLYURETHANE HOT-MELT ADHESIVES HAVING A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2013-11-21 | — | — | WO | claimed |
| EP-2664637-A1 | Reactive polyurethane hot melt adhesives with low isocyanate monomer content | Sika Technology AG (CH) | 2013-11-20 | — | — | EP | claimed |
| EP-2895517-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | disclosed |
| EP-2895517-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | Sika Technology AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014040922-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2014-03-20 | — | — | WO | disclosed |
| EP-2706073-A1 | Two-component polyurethane composition | Sika Technology AG (CH) | 2014-03-12 | — | — | EP | disclosed |
| WO-2013171200-A1 | REACTIVE POLYURETHANE HOT-MELT ADHESIVES HAVING A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2013-11-21 | — | — | WO | disclosed |
| EP-2664637-A1 | Reactive polyurethane hot melt adhesives with low isocyanate monomer content | Sika Technology AG (CH) | 2013-11-20 | — | — | EP | disclosed |
| US-4578395-A | Certain aralkylaminoalkyl esters of 1,4 dihydropyridines as antihypertensive | TEIJIN LIMITED (JP) | 1986-03-25 | — | — | US | disclosed |
| EP-0128010-A2 | 1,4-Dihydropyridine derivative, process for production thereof and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |