Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721500 | 0.79 | POLB (0.63) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7102086 | 0.73 | APAF1 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16756532 | 0.70 | KMT2A (0.62) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16756383 | 0.70 | KMT2A (0.62) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30037937 | 0.70 | RAB9A (0.62) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL757031 | 0.70 | RAB9A (0.62) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL762447 | 0.69 | MAPK1 (0.66) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19073862 | 0.68 | NOS2 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL27582818 | 0.68 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL757030 | 0.68 | MAPT (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064414-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB. (SE) | 2003-08-07 | — | — | WO | disclosed |