Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086411 | 0.85 | P2RX7 (0.52) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL27677548 | 0.77 | NAPRT (0.50) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL108190 | 0.77 | — | — | |
| SCHEMBL6556263 | 0.76 | P2RX7 (0.50) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL27638967 | 0.74 | NAPRT (0.48) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL27936995 | 0.74 | NAPRT (0.48) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL27821532 | 0.74 | NAPRT (0.48) | P2RX7CTNNB1WNT3ACES2CES1 | |
| Bromide SCHEMBL5264768 | 0.74 | NAPRT (0.48) | P2RX7CTNNB1WNT3ACES2CES1 | |
| Hydrochloric Acid SCHEMBL2553231 | 0.74 | NAPRT (0.48) | P2RX7CTNNB1WNT3ACES2CES1 | |
| SCHEMBL7483687 | 0.74 | P2RX7 (0.43) | P2RX7CTNNB1WNT3ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211190-B1 | Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | claimed |
| US-10245330-B2 | Compositions and methods for imaging | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-02 | — | — | US | disclosed |
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-19 | — | — | US | disclosed |
| US-20130209360-A1 | Compositions and Methods for Imaging | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2012027274-A2 | COMPOSITIONS AND METHODS FOR IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-01 | — | — | WO | disclosed |
| US-6211190-B1 | Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10245330-B2 | Compositions and methods for imaging | GPX4, PRDX5, PRDX2 | P2RX7 2019/4885CTNNB1 2979/4885WNT3A 3425/4885 |
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | GPX4, PRDX5, PRDX2 | P2RX7 2019/4885CTNNB1 2979/4885WNT3A 3425/4885 |
| US-20130209360-A1 | Compositions and Methods for Imaging | GPX4, PRDX5, PRDX2 | P2RX7 2019/4885CTNNB1 2979/4885WNT3A 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.