Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871173 | 0.82 | KDM2B (0.40) | HTR2AGAA | |
| SCHEMBL3107572 | 0.77 | MAPT (0.50) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL30672091 | 0.73 | CA12 (0.55) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL6568800 | 0.73 | CA12 (0.55) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL27629282 | 0.71 | MAPT (0.36) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL10967544 | 0.64 | CA12 (0.41) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL29219227 | 0.64 | POLB (0.43) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL28706031 | 0.63 | POLB (0.53) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL28320396 | 0.63 | KCNMA1 (0.44) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL2052186 | 0.62 | CYP1A2 (0.38) | KDM4EKMT2AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003042160-A1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2003-05-22 | — | — | WO | disclosed |