Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195893 | 0.80 | RAB9A (0.56) | HPGDALDH1A1CA12CA9SMN1; SMN2 | |
| SCHEMBL30804587 | 0.80 | RAB9A (0.56) | HPGDALDH1A1CA12CA9SMN1; SMN2 | |
| SCHEMBL6581393 | 0.79 | CA12 (0.52) | KDM4EALDH1A1CA12CA9BRD4 | |
| SCHEMBL10662835 | 0.77 | CA12 (0.53) | KDM4EALDH1A1CA12CA9BRD4 | |
| SCHEMBL6568800 | 0.74 | CA12 (0.55) | HPGDKDM4EALDH1A1CA12CA9 | |
| SCHEMBL30672091 | 0.74 | CA12 (0.55) | HPGDKDM4EALDH1A1CA12CA9 | |
| SCHEMBL1366107 | 0.74 | MAOB (0.60) | HPGDKDM4EALDH1A1CA12CA9 | |
| SCHEMBL1368083 | 0.74 | CA12 (0.60) | CA12CA9CA1CA2CA4 | |
| SCHEMBL5722231 | 0.71 | ADORA3 (0.48) | KDM4EALDH1A1CA12CA9SMN1; SMN2 | |
| SCHEMBL30321500 | 0.70 | CA12 (0.50) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143918-A | - 2 (1H)-quinolinone activity skeleton of 3,4- dihydro -3- (2- (2-hydroxybenzoyl)) and synthetic method and application | 青岛农业大学 | 2019-08-20 | — | — | CN | disclosed |