Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135988 | 0.85 | DRD2 (0.40) | DRD2DRD4DRD3PGRAR | |
| SCHEMBL5134381 | 0.84 | DRD2 (0.43) | DRD2DRD4DRD3PGRAR | |
| SCHEMBL5134514 | 0.77 | DYRK1A (0.42) | CLK1CLK2CLK3DYRK1AMELK | |
| SCHEMBL5137505 | 0.77 | DRD2 (0.39) | DRD2DRD4DRD3HPGDMAPT | |
| SCHEMBL21331550 | 0.76 | ALDH1A1 (0.43) | EGFRALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL5069629 | 0.74 | SMN1; SMN2 (0.37) | CLK1CLK2CLK3DYRK1AMELK | |
| SCHEMBL20435262 | 0.72 | APP (0.47) | DRD2DRD4DRD3PGRAR | |
| SCHEMBL852452 | 0.72 | GRM5 (0.49) | CLK1CLK2CLK3DYRK1AMELK | |
| SCHEMBL29636414 | 0.72 | GRM5 (0.49) | CLK1CLK2CLK3DYRK1AMELK | |
| SCHEMBL10535351 | 0.72 | TSHR (0.45) | ALDH1A1HSD17B10HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030058697-A1 | Programmable molecular device | NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA OFFICE OF NAVAL RESEARCH | 2003-03-27 | — | — | US | disclosed |