Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710893 | 0.83 | CES2 (0.53) | PIK3CAMTORMLYCDTRPM8 | |
| SCHEMBL21516873 | 0.83 | MAP2K1 (0.52) | MAP2K1MAP2K2PIK3CAMTORGPR27 | |
| SCHEMBL23003420 | 0.82 | PDK2 (0.42) | PIK3CAMTORMLYCDGPR119TRPM8 | |
| SCHEMBL20982579 | 0.82 | MLYCD (0.49) | PIK3CAMTORMLYCDGPR119CLK1 | |
| SCHEMBL29688875 | 0.82 | PIK3CA (0.43) | PIK3CAMTORMLYCDGPR119CLK1 | |
| SCHEMBL12121067 | 0.82 | PIK3CA (0.43) | PIK3CAMTORMLYCDGPR119CLK1 | |
| SCHEMBL30514003 | 0.81 | CPS1 (0.55) | CLK1DYRK1ADYRK1B | |
| SCHEMBL152537 | 0.81 | DGAT1 (0.53) | MAP2K1PIK3CAMTORMLYCD | |
| SCHEMBL2645212 | 0.81 | PIK3CA (0.45) | PIK3CAMTORMLYCDGPR119CLK1 | |
| SCHEMBL24452660 | 0.81 | PIK3CA (0.40) | PIK3CAMTORMLYCDGPR119CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835252-B1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RES & DEV (IE) | 2003-07-30 | — | — | EP | disclosed |
| US-6015825-A | Triazole antifungal agents | PFIZER INC. (US) | 2000-01-18 | — | — | US | disclosed |
| WO-1997001552-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-01-16 | — | — | WO | disclosed |