SCHEMBL7265145

SCHEMBL7265145

Cc1ccc(S(=O)(=O)OCCCC(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
STAT3 P40763 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
PSMD10 O75832 1/20 0.45
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 3/20 0.44
PPARG P37231 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.42
SIRT5 Q9NXA8 1/20 0.42
POLB P06746 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
RAB9A P51151 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238329 0.95 STAT3 (0.47) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL9458218 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL8863706 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL30850377 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL17614843 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL25030574 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL8864017 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL7827739 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL9764712 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A
SCHEMBL10449020 0.94 STAT3 (0.46) TSHRSTAT3L3MBTL1PSMD10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219932-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
EP-0222413-B1 NOVEL FORSKOLIN DERIVATIVES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-02-05 EP disclosed
US-4954642-A INOTROPIC, HYPOTENSIVE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-09-04 US disclosed
EP-0222413-A2 Novel forskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219932-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME BMP1, BMP2, NPSR1 TSHR 685/4885STAT3 2111/4885L3MBTL1 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.