Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187288 | 0.93 | ALDH1A1 (0.80) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL9570228 | 0.91 | ALDH1A1 (0.96) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL7502802 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL8134520 | 0.81 | ALDH1A1 (0.73) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL22502146 | 0.81 | GAA (0.54) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL7991256 | 0.80 | ATM (0.70) | ALDH1A1GAAKDM4ETSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL22502140 | 0.80 | GAA (0.57) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL1130003 | 0.80 | KDM4E (0.57) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL20969213 | 0.80 | ACHE (0.61) | ALDH1A1GAAKDM4EMAPTMAPK1 | |
| SCHEMBL18120293 | 0.80 | CA12 (0.61) | ALDH1A1GAAKDM4EMAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000806-A1 | AMIDES OF CYCLIC AMINO ACIDS USED AS PDE 4 INHIBITORS | ELBION AG (DE) | 2003-12-31 | — | — | WO | claimed |
| CN-113563244-B | Substituted aza five-membered ring compound and application thereof in medicine | 广东东阳光药业股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-113563244-A | Substituted aza five-membered ring compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-10-29 | — | — | CN | disclosed |