SCHEMBL726588

SCHEMBL726588

Cc1cc(-c2cc(C)c(O)c(C)c2)cc(C)c1[O]

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.74
CA2 P00918 1/20 0.74
CYP2C9 P11712 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 1/20 0.48
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2B6 P20813 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 4/20 0.38
EEF2K O00418 1/20 0.38
SRC P12931 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22804025 0.86 CA1 (1.00) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL220910 0.86 CA1 (1.00) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL9579782 0.83 CA1 (0.64) CA1CA2CYP2C9CYP1A2CYP2C19
Methane SCHEMBL28825813 0.83 CA1 (0.93) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL673373 0.83 CA1 (0.93) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL17060490 0.78 CA1 (0.82) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL15140191 0.77 CA1 (0.70) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL9229319 0.76 CA2 (0.78) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL19126271 0.76 CA1 (0.78) CA1CA2CYP2C9CYP1A2CYP2C19
SCHEMBL3123299 0.75 CA1 (0.58) CA1CA2CYP2C9CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2723802-A2 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC Innovative Plastics IP B.V. (NL) 2014-04-30 EP claimed
US-8669332-B2 Poly(arylene ether)-polysiloxane composition and method SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-03-11 US claimed
WO-2013003038-A2 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-01-03 WO claimed
US-20120329961-A1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-12-27 US claimed
CN-115315460-B Poly (phenylene ether) composition, method of making the same, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2024-05-28 CN disclosed
EP-2917283-B1 REINFORCED POLY(PHENYLENE ETHER)-POLYSILOXANE BLOCK COPOLYMER COMPOSITION, AND ARTICLE COMPRISING SAME SHPP GLOBAL TECH BV (NL) 2024-04-03 EP disclosed
US-20230174781-A1 POLY(PHENYLENE ETHER) COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-06-08 US disclosed
EP-4121475-A1 POLY(PHENYLENE ETHER) COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES MADE THEREFROM SHPP Global Technologies B.V. (NL) 2023-01-25 EP disclosed
CN-115315460-A Poly (phenylene ether) composition, method of making, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2022-11-08 CN disclosed
WO-2021186252-A1 POLY(PHENYLENE ETHER) COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-23 WO disclosed
EP-3294809-B1 REINFORCED POLY(PHENYLENE ETHER) COMPOSITIONS, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECH BV (NL) 2021-08-11 EP disclosed
CN-107548408-B Reinforced poly (phenylene ether) compositions and articles prepared therefrom 沙特基础工业全球技术有限公司 2020-02-18 CN disclosed
US-20110152431-A1 FLAME RETARDANT POLYAMIDE COMPOSITION, METHOD, AND ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110152420-A1 POLY(ARYLENE ETHER)/POLYAMIDE COMPOSITIONS, METHODS, AND ARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
EP-2297247-A2 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC Innovative Plastics IP B.V. (NL) 2011-03-23 EP disclosed
US-7847032-B2 Poly(arylene ether) composition and extruded articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-12-07 US disclosed
WO-2010068362-A2 POLY(ARYLENE ETHER) COMPOSITION AND EXTRUDED ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-06-17 WO disclosed
US-20100139944-A1 POLY(ARYLENE ETHER) COMPOSITION AND EXTRUDED ARTICLES DERIVED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-06-10 US disclosed
WO-2010008683-A2 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-21 WO disclosed
US-20090318635-A1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-24 US disclosed