Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.64 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.64 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.64 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | FURIN | P09958 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742691 | 1.00 | PARP10 (0.64) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL10496906 | 0.93 | TNKS (0.60) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL10782197 | 0.93 | AKR1C3 (0.70) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL9769579 | 0.92 | PARP10 (0.58) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL726592 | 0.92 | AKR1C3 (0.62) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL1193379 | 0.91 | AKR1C3 (0.72) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL10933601 | 0.90 | AKR1C3 (0.60) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL11217963 | 0.88 | AKR1C3 (0.54) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL19612714 | 0.86 | NAAA (0.56) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL10496995 | 0.85 | HTT (0.55) | PARP10TNKSPARP15PARP14TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357753-B2 | Screen-printable encapsulants based on polyhydroxyamides that thermally convert to polybenzoxazoles | CDA PROCESSING LIMITED LIABILITY COMPANY (US) | 2013-01-22 | — | — | US | claimed |
| US-8309655-B2 | Methods for the preparation of a poly(arylene ether) polysiloxane multiblock copolymer, multiblock copolymers produced thereby, and associated compositions and articles | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-11-13 | — | — | US | claimed |
| EP-2516501-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER | SABIC Innovative Plastics IP B.V. (NL) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077297-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-06-30 | — | — | WO | claimed |
| US-20110152471-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER, MULTIBLOCK COPOLYMERS PRODUCED THEREBY, AND ASSOCIATED COMPOSITIONS AND ARTICLES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2011-06-23 | — | — | US | claimed |
| WO-2023223738-A1 | METHOD FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, METHOD FOR DETERMINING MOLDABILITY OF THERMOPLASTIC RESIN COMPOSITION, AND THERMOPLASTIC RESIN COMPOSITION FOR MOLDING AT TEMPERATURE THAT IS NOT LESS THAN DECOMPOSITION TEMPERATURE OF ELASTOMER | ポリプラスチックス株式会社 | 2023-11-23 | — | — | WO | disclosed |
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-28 | — | — | US | disclosed |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-21 | — | — | US | disclosed |
| EP-2588656-B1 | POLYAMIDE-POLY(ARYLENE ETHER) FIBER AND METHOD FOR ITS PREPARATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-01-09 | — | — | EP | disclosed |
| US-10113055-B2 | Article comprising poly(phenylene ether)-polysiloxane copolymer composition | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-10-30 | — | — | US | disclosed |
| US-9896545-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-02-20 | — | — | US | disclosed |
| US-20180022872-A1 | BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-01-25 | — | — | US | disclosed |
| EP-0247889-B1 | HIGH MODULUS POLY-P-PHENYLENE TEREPHTHALAMIDE FIBER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5028372-A | Anisotropic Liquid Solution | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-5001219-A | High modulus poly-p-phenylene terephthalamide fiber | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0348996-A2 | Method and apparatus for producing para-aramid pulp and pulp produced thereby | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4883634-A | WATER SWELLING, DRYING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4737571-A | REACTING PHENYLENEDIAMINE WITH TEREPHTHALOYL CHLORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| US-4684409-A | SOLUTION POLYMERIZATION OF AROMATIC POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0229714-A2 | Polymerization of aromatic polyamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | WASF2, PBRM1, WEE1 | PARP10 644/4885TNKS 775/4885PARP15 457/4885 |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | PARN, PAICS, PAM | PARP10 350/4885TNKS 304/4885PARP15 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.