SCHEMBL7266183

SCHEMBL7266183

Cc1ccc(S(=O)(=O)OCC(OC2CCCCO2)c2ccc(N)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC12A2 P55011 1/20 0.34
SLC12A5 Q9H2X9 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
GAA P10253 3/20 0.31
POLB P06746 1/20 0.31
ENPP3 O14638 2/20 0.31
ENPP1 P22413 2/20 0.31
ENPP2 Q13822 2/20 0.31
CYP2C19 P33261 1/20 0.31
TP53 P04637 1/20 0.31
ALDH1A1 P00352 3/20 0.31
TSHR P16473 3/20 0.31
CYP3A4 P08684 1/20 0.31
HTT P42858 2/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
F2 P00734 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7266175 0.95 SLC12A2 (0.37) SLC12A2SLC12A5CHRM2CHRM1GAA
SCHEMBL7266212 0.90 GAA (0.35) SLC12A2SLC12A5CHRM2CHRM1GAA
SCHEMBL5157122 0.89 SLC6A3 (0.37) SLC12A2SLC12A5CYP2C19ALDH1A1CYP3A4
SCHEMBL5160747 0.89 SLC6A3 (0.37) SLC12A2SLC12A5CYP2C19ALDH1A1CYP3A4
SCHEMBL5157441 0.89 SLC6A3 (0.37) SLC12A2SLC12A5CYP2C19ALDH1A1CYP3A4
SCHEMBL7266216 0.89 ALDH1A1 (0.39) CHRM2CHRM1GAAENPP3ENPP1
SCHEMBL7261726 0.88 ALDH1A1 (0.38) SLC12A2SLC12A5CHRM2CHRM1GAA
SCHEMBL7265009 0.87 ACHE (0.35) GAAALDH1A1HSD17B10
SCHEMBL14730117 0.86 SLC12A2 (0.31) SLC12A2SLC12A5CHRM2CHRM1GAA
SCHEMBL5157375 0.85 MEN1 (0.34) SLC12A2SLC12A5CHRM2CHRM1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642395-B1 Esterifying mandelic acid derivative; protecting hydroxyl group and reducing ester; sulfonating and epoxidizing MITSUBISHI RAYON CO., LTD. (JP) 2003-11-04 US disclosed
EP-1236714-A1 ACETALSULFONATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING STYRENE OXIDE DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2002-09-04 EP disclosed