Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSH | P09668 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264476 | 1.00 | CTSK (0.53) | CTSKCTSLCTSBCTSHHTT | |
| SCHEMBL5980007 | 1.00 | CTSK (0.53) | CTSKCTSLCTSBCTSHHTT | |
| Sulfuric Acid SCHEMBL7274239 | 0.96 | CTSK (0.49) | CTSKCTSLCTSBCTSHHTT | |
| Sulfuric Acid SCHEMBL7272355 | 0.96 | CTSK (0.49) | CTSKCTSLCTSBCTSHHTT | |
| SCHEMBL9135873 | 0.91 | HTT (0.46) | CTSKCTSLCTSBCTSHHTT | |
| SCHEMBL9135888 | 0.91 | HTT (0.46) | CTSKCTSLCTSBCTSHHTT | |
| SCHEMBL29959455 | 0.87 | CTSL (0.48) | CTSLSIRT2 | |
| Hydrochloric Acid SCHEMBL11145577 | 0.87 | PSMB1 (0.61) | CTSKCTSLCTSBPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL11141841 | 0.86 | PSMB1 (0.61) | CTSKCTSLCTSBPSMB1PSMB5 | |
| SCHEMBL24152311 | 0.86 | FOLH1 (0.58) | CTSKHTTTGM2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185390-B1 | TRIPEPTIDYL-ARGININALDEHYDE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS THEREOF, AS WELL AS N-(MONOALKYL) AND N,N-DI-(ALKYL)-XXX-L-PROLINE DIPEPTIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-10-02 | — | — | EP | disclosed |
| EP-0185390-A2 | Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as N-(monoalkyl) and N,N-di-(alkyl)-Xxx-L-proline dipeptide | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-06-25 | — | — | EP | disclosed |