Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267485 | 0.87 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7272104 | 0.85 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7267660 | 0.84 | CACNA1F (0.48) | CACNA1B | |
| SCHEMBL7272327 | 0.84 | CACNA1F (0.60) | CACNA1B | |
| SCHEMBL7266744 | 0.84 | CACNA1F (0.48) | CACNA1B | |
| SCHEMBL4503644 | 0.83 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL7272429 | 0.81 | CACNA1B (0.41) | CACNA1B | |
| SCHEMBL7267403 | 0.81 | ALDH1A1 (0.40) | CACNA1B | |
| SCHEMBL7275738 | 0.80 | TSHR (0.52) | CACNA1B | |
| SCHEMBL7275522 | 0.79 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |